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RSG1

GENERAL INFORMATION

Gene name

 RSG1

Gene description

 REM2 and RAB-like small GTPase 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, Splice and/or transcript discrepancy exists.

Reliability score

 Approved based on 1 antibody.
HPA028453
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA028453

GENE INFORMATION

Gene name

 RSG1 (HGNC Symbol)

Synonyms

 C1orf89, MGC10731

Description

 REM2 and RAB-like small GTPase 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p36.13

Chromosome location (bp)

 16231700 - 16237162

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132881 (version 83.38)

Entrez gene

 79363

UniProt

 Q9BU20 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BU20

Antibodypedia

 RSG1 antibodies

PROTEIN BROWSER
RSG1-001
RSG1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RSG1-001
ENSP00000364749
ENST00000375599
Q9BU20 [Direct mapping]
REM2- and Rab-like small GTPase 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006887 [exocytosis]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0017157 [regulation of exocytosis]
GO:0031338 [regulation of vesicle fusion]
GO:0034613 [cellular protein localization]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
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 258 aa
28.5 kDa 		No 0
RSG1-003
ENSP00000406390
ENST00000434014
H0Y6L8 [Direct mapping]
REM2- and Rab-like small GTPase 1
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Predicted intracellular proteins
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GO:0005525 [GTP binding]
GO:0007264 [small GTPase mediated signal transduction]
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 112 aa
12.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.