Cell atlas - BEX2 - The Human Protein Atlas

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BEX2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	BEX2
Gene description	Brain expressed X-linked 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SCLC-21H, NTERA-2, hTCEpi, SH-SY5Y)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, NTERA-2, hTCEpi, SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	BEX2 (HGNC Symbol)
Synonyms	DJ79P11.1
Description	Brain expressed X-linked 2 (HGNC Symbol)
Entrez gene summary	This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Chromosome	X
Cytoband	q22.2
Chromosome location (bp)	103309346 - 103311046
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133134 (version 83.38)
Entrez gene	84707
UniProt	Q9BXY8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXY8
Antibodypedia	BEX2 antibodies

PROTEIN BROWSER

BEX2-001	BEX2-002	BEX2-003	BEX2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BEX2-001 ENSP00000394915 ENST00000449185	X6RDN0 [Direct mapping] Protein BEX2 Show all	Predicted intracellular proteins Show all		101 aa 12.2 kDa	No	0
BEX2-002 ENSP00000361762 ENST00000372677	Q9BXY8 [Direct mapping] Protein BEX2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0007049 [cell cycle] GO:0042981 [regulation of apoptotic process] GO:0051726 [regulation of cell cycle] Show all	128 aa 15.3 kDa	No	0
BEX2-003 ENSP00000361759 ENST00000372674	Q9BXY8 [Direct mapping] Protein BEX2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0007049 [cell cycle] GO:0042981 [regulation of apoptotic process] GO:0051726 [regulation of cell cycle] Show all	128 aa 15.3 kDa	No	0
BEX2-201 ENSP00000442521 ENST00000536889	Q9BXY8 [Direct mapping] Protein BEX2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006915 [apoptotic process] GO:0007049 [cell cycle] GO:0042981 [regulation of apoptotic process] GO:0051726 [regulation of cell cycle] Show all	160 aa 18.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.