Expression of BTBD2 in cancer - Summary - The Human Protein Atlas

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BTBD2

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	BTBD2
Gene description	BTB (POZ) domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	BTBD2
Synonyms
Description	BTB (POZ) domain containing 2 (HGNC Symbol)
Entrez gene summary	The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	1985438 - 2034881
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133243 (version 83.38)
Entrez gene	55643
UniProt	Q9BX70 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BX70
Antibodypedia	BTBD2 antibodies

PROTEIN BROWSER

BTBD2-001	BTBD2-004	BTBD2-005	BTBD2-006	BTBD2-010	BTBD2-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BTBD2-001 ENSP00000255608 ENST00000255608	Q9BX70 [Direct mapping] BTB/POZ domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000932 [cytoplasmic mRNA processing body] GO:0005515 [protein binding] Show all	525 aa 55.9 kDa	No	0
BTBD2-004 ENSP00000481529 ENST00000590646	A0A087WY57 [Direct mapping] BTB/POZ domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	53 aa 5.8 kDa	No	0
BTBD2-005 ENSP00000483892 ENST00000587742	A0A087X147 [Direct mapping] BTB/POZ domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	35 aa 3.8 kDa	No	0
BTBD2-006 ENSP00000478992 ENST00000588395	A0A087WUX2 [Direct mapping] BTB/POZ domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		25 aa 2.6 kDa	No	0
BTBD2-010 ENSP00000481163 ENST00000592082	A0A087WXN3 [Direct mapping] BTB/POZ domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		116 aa 13 kDa	No	0
BTBD2-011 ENSP00000467113 ENST00000587825	K7ENV9 [Direct mapping] BTB/POZ domain-containing protein 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	321 aa 36.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.