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CSNK1G2

GENERAL INFORMATION

Gene name

 CSNK1G2

Gene description

 Casein kinase 1, gamma 2

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in glandular cells.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA034868 , HPA056572
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Pancreatic cancer

STAINING SUMMARY
HPA034868
HPA056572

GENE INFORMATION

Gene name

 CSNK1G2 (HGNC Symbol)

Synonyms

 CK1g2

Description

 Casein kinase 1, gamma 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 1941149 - 1981338

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133275 (version 83.38)

Entrez gene

 1455

UniProt

 P78368 (UniProt - Evidence at protein level)

neXtProt

 NX_P78368

Antibodypedia

 CSNK1G2 antibodies

PROTEIN BROWSER
CSNK1G2-001
CSNK1G2-002
CSNK1G2-004
CSNK1G2-005
CSNK1G2-007
CSNK1G2-008
CSNK1G2-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CSNK1G2-001
ENSP00000255641
ENST00000255641
P78368 [Direct mapping]
Casein kinase I isoform gamma-2
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CK1 Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000287 [magnesium ion binding]
GO:0001948 [glycoprotein binding]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006468 [protein phosphorylation]
GO:0006665 [sphingolipid metabolic process]
GO:0006897 [endocytosis]
GO:0007165 [signal transduction]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0030148 [sphingolipid biosynthetic process]
GO:0042277 [peptide binding]
GO:0044281 [small molecule metabolic process]
GO:0046777 [protein autophosphorylation]
GO:0051219 [phosphoprotein binding]
GO:0090263 [positive regulation of canonical Wnt signaling pathway]
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 415 aa
47.5 kDa 		No 0
CSNK1G2-002
ENSP00000465106
ENST00000589350
K7EJC0 [Direct mapping]
Casein kinase I isoform gamma-2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005737 [cytoplasm]
GO:0006897 [endocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
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 84 aa
9 kDa 		No 0
CSNK1G2-004
ENSP00000467214
ENST00000591752
K7EP38 [Direct mapping]
Casein kinase I isoform gamma-2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006897 [endocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
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 76 aa
8.1 kDa 		No 0
CSNK1G2-005
ENSP00000480052
ENST00000585957
A0A087WW97 [Direct mapping]
Casein kinase I isoform gamma-2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0006897 [endocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
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 101 aa
11.8 kDa 		No 0
CSNK1G2-007
ENSP00000468637
ENST00000589385
K7ESB6 [Direct mapping]
Casein kinase I isoform gamma-2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006897 [endocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
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 299 aa
33.6 kDa 		No 0
CSNK1G2-008
ENSP00000480185
ENST00000585959
A0A087WWF5 [Direct mapping]
Casein kinase I isoform gamma-2
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006897 [endocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
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 235 aa
26.4 kDa 		No 0
CSNK1G2-009
ENSP00000480929
ENST00000591002
A0A087WXD7 [Direct mapping]
Casein kinase I isoform gamma-2
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0006897 [endocytosis]
GO:0008360 [regulation of cell shape]
GO:0016055 [Wnt signaling pathway]
GO:0018105 [peptidyl-serine phosphorylation]
Show all
 206 aa
22.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.