Expression of FOPNL in cancer - Summary

GENERAL INFORMATION
Gene name	FOPNL
Gene description	FGFR1OP N-terminal like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expressed in cilia in the fallopian tube and airway epithelia, and in the cytoplasm of most cell types.

ANTIBODY IHC RELIABILITY
Data reliability description	External characterization data supports antibody staining.
Reliability score	Supported based on 1 antibody. HPA040599
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA040599

GENE INFORMATION
Gene name	FOPNL (HGNC Symbol)
Synonyms	C16orf63, DKFZp686N1651, FLJ31153, FOR20, PHSECRG2
Description	FGFR1OP N-terminal like (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.11
Chromosome location (bp)	15865720 - 15888625
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133393 (version 83.38)
Entrez gene	123811
UniProt	Q96NB1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96NB1
Antibodypedia	FOPNL antibodies

PROTEIN BROWSER

FOPNL-001	FOPNL-002	FOPNL-005	FOPNL-006	FOPNL-007	FOPNL-008	FOPNL-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FOPNL-001 ENSP00000255759 ENST00000255759	Q96NB1 [Direct mapping] LisH domain-containing protein FOPNL Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005815 [microtubule organizing center] GO:0031514 [motile cilium] GO:0034451 [centriolar satellite] GO:0034453 [microtubule anchoring] GO:0036064 [ciliary basal body] GO:0042384 [cilium assembly] Show all	174 aa 19.8 kDa	No	0
FOPNL-002 ENSP00000460312 ENST00000573968	Q96NB1 [Direct mapping] LisH domain-containing protein FOPNL Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0005815 [microtubule organizing center] GO:0031514 [motile cilium] GO:0034451 [centriolar satellite] GO:0034453 [microtubule anchoring] GO:0036064 [ciliary basal body] GO:0042384 [cilium assembly] Show all	100 aa 11.5 kDa	No	0
FOPNL-005 ENSP00000461830 ENST00000573429	I3NI25 [Direct mapping] LisH domain-containing protein FOPNL Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005813 [centrosome] GO:0031514 [motile cilium] GO:0036064 [ciliary basal body] Show all	198 aa 22.1 kDa	No	0
FOPNL-006 ENSP00000459429 ENST00000575744	I3L269 [Direct mapping] LisH domain-containing protein FOPNL Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005813 [centrosome] Show all	108 aa 12.1 kDa	No	0
FOPNL-007 ENSP00000459804 ENST00000575073	I3L2N4 [Direct mapping] LisH domain-containing protein FOPNL Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005815 [microtubule organizing center] GO:0034453 [microtubule anchoring] Show all	104 aa 11.9 kDa	No	0
FOPNL-008 ENSP00000461548 ENST00000573396	I3L4V2 [Direct mapping] LisH domain-containing protein FOPNL Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	128 aa 14.2 kDa	No	0
FOPNL-009 ENSP00000458348 ENST00000575938	I3L0U4 [Direct mapping] LisH domain-containing protein FOPNL Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005815 [microtubule organizing center] GO:0034453 [microtubule anchoring] Show all	124 aa 14 kDa	No	0