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GSC

GENERAL INFORMATION

Gene name

 GSC

Gene description

 Goosecoid homeobox

Protein class

 Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (HEK93, MCF7, REH, SH-SY5Y, T-47d, U-251 MG)
HPA (normal tissue):Tissue enhanced (adipose tissue)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 GSC

Synonyms

Description

 Goosecoid homeobox (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. [provided by RefSeq, Jul 2008]

Chromosome

 14

Cytoband

 q32.13

Chromosome location (bp)

 94768216 - 94770230

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133937 (version 83.38)

Entrez gene

 145258

UniProt

 P56915 (UniProt - Evidence at protein level)

neXtProt

 NX_P56915

Antibodypedia

 GSC antibodies

PROTEIN BROWSER
GSC-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GSC-001
ENSP00000238558
ENST00000238558
P56915 [Direct mapping]
Homeobox protein goosecoid
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001103 [RNA polymerase II repressing transcription factor binding]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007369 [gastrulation]
GO:0009653 [anatomical structure morphogenesis]
GO:0014036 [neural crest cell fate specification]
GO:0021904 [dorsal/ventral neural tube patterning]
GO:0023019 [signal transduction involved in regulation of gene expression]
GO:0030178 [negative regulation of Wnt signaling pathway]
GO:0030900 [forebrain development]
GO:0042474 [middle ear morphogenesis]
GO:0043565 [sequence-specific DNA binding]
GO:0043583 [ear development]
GO:0048644 [muscle organ morphogenesis]
GO:0048704 [embryonic skeletal system morphogenesis]
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 257 aa
28.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.