Expression of CATSPERB in cancer - Summary - The Human Protein Atlas

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CATSPERB

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CATSPERB
Gene description	Catsper channel auxiliary subunit beta
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA035134
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA035134

GENE INFORMATION
Gene name	CATSPERB (HGNC Symbol)
Synonyms	C14orf161, FLJ14298
Description	Catsper channel auxiliary subunit beta (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.12
Chromosome location (bp)	91580696 - 91780707
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133962 (version 83.38)
Entrez gene	79820
UniProt	Q9H7T0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H7T0
Antibodypedia	CATSPERB antibodies

PROTEIN BROWSER

CATSPERB-001	CATSPERB-003	CATSPERB-004	CATSPERB-005	CATSPERB-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CATSPERB-001 ENSP00000256343 ENST00000256343	Q9H7T0 [Direct mapping] Cation channel sperm-associated protein subunit beta Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005929 [cilium] GO:0007275 [multicellular organismal development] GO:0007338 [single fertilization] GO:0032504 [multicellular organism reproduction] GO:0035036 [sperm-egg recognition] GO:0036128 [CatSper complex] GO:0048240 [sperm capacitation] Show all	1116 aa 126.9 kDa	Yes	3
CATSPERB-003 ENSP00000450878 ENST00000553329	G3V2V0 [Direct mapping] Cation channel sperm-associated protein subunit beta Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0036128 [CatSper complex] Show all	150 aa 17.1 kDa	No	0
CATSPERB-004 ENSP00000452224 ENST00000554560	G3V584 [Direct mapping] Cation channel sperm-associated protein subunit beta Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0036128 [CatSper complex] Show all	100 aa 11.3 kDa	No	0
CATSPERB-005 ENSP00000451047 ENST00000553676	G3V352 [Direct mapping] Cation channel sperm-associated protein subunit beta Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0036128 [CatSper complex] Show all	74 aa 8.6 kDa	No	0
CATSPERB-006 ENSP00000451455 ENST00000556661	G3V352 [Direct mapping] Cation channel sperm-associated protein subunit beta Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0036128 [CatSper complex] Show all	74 aa 8.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.