Expression of COX16 in cancer - Summary - The Human Protein Atlas

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COX16

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	COX16
Gene description	COX16 cytochrome c oxidase assembly homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene. Antibody staining in cells/structures not annotated, view images.
Reliability score	Uncertain based on 1 antibody. HPA062659
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA062659

GENE INFORMATION
Gene name	COX16 (HGNC Symbol)
Synonyms	C14orf112, HSPC203
Description	COX16 cytochrome c oxidase assembly homolog (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.2
Chromosome location (bp)	70325081 - 70359731
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133983 (version 83.38)
Entrez gene	51241
UniProt	Q9P0S2 (UniProt - Inferred from homology)
neXtProt	NX_Q9P0S2
Antibodypedia	COX16 antibodies

PROTEIN BROWSER

COX16-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COX16-001 ENSP00000374562 ENST00000389912	Q9P0S2 [Direct mapping] Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial B8XYC5 [Target identity:100%; Query identity:100%] Cytochrome c oxidase assembly factor isoform 1; Cytochrome c oxidase assembly factor isoform 2 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] GO:0031966 [mitochondrial membrane] Show all	106 aa 12.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.