Expression of ANKRD16 in cancer - Summary - The Human Protein Atlas

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ANKRD16

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANKRD16
Gene description	Ankyrin repeat domain 16
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA037920 , HPA037921
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and pancreatic cancer (favourable).
Renal cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037920	HPA037921

GENE INFORMATION
Gene name	ANKRD16 (HGNC Symbol)
Synonyms	DKFZP434N1511
Description	Ankyrin repeat domain 16 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	p15.1
Chromosome location (bp)	5861617 - 5889906
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134461 (version 83.38)
Entrez gene	54522
UniProt	Q6P6B7 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P6B7
Antibodypedia	ANKRD16 antibodies

PROTEIN BROWSER

ANKRD16-001	ANKRD16-002	ANKRD16-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD16-001 ENSP00000369434 ENST00000380092	Q6P6B7 [Direct mapping] Ankyrin repeat domain-containing protein 16 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	361 aa 39.3 kDa	No	0
ANKRD16-002 ENSP00000352361 ENST00000191063	Q6P6B7 [Direct mapping] Ankyrin repeat domain-containing protein 16 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	304 aa 33.4 kDa	No	0
ANKRD16-003 ENSP00000369436 ENST00000380094	Q6P6B7 [Direct mapping] Ankyrin repeat domain-containing protein 16 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	361 aa 39.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.