Expression of TMEM241 in cancer - Summary - The Human Protein Atlas

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TMEM241

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM241
Gene description	Transmembrane protein 241
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA059922
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (unfavourable).
Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA059922

GENE INFORMATION
Gene name	TMEM241 (HGNC Symbol)
Synonyms	C18orf45, FLJ44259, MGC11386
Description	Transmembrane protein 241 (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q11.2
Chromosome location (bp)	23197144 - 23437961
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134490 (version 83.38)
Entrez gene	85019
UniProt	Q24JQ0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q24JQ0
Antibodypedia	TMEM241 antibodies

PROTEIN BROWSER

TMEM241-001	TMEM241-011	TMEM241-012	TMEM241-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM241-001 ENSP00000372720 ENST00000383233	Q24JQ0 [Direct mapping] Transmembrane protein 241 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0005338 [nucleotide-sugar transmembrane transporter activity] GO:0006486 [protein glycosylation] GO:0015297 [antiporter activity] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] GO:1990570 [GDP-mannose transmembrane transport] Show all	296 aa 32.6 kDa	No	9
TMEM241-011 ENSP00000464174 ENST00000578520	J3QRE6 [Direct mapping] Transmembrane protein 241 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005338 [nucleotide-sugar transmembrane transporter activity] GO:0006486 [protein glycosylation] GO:0015297 [antiporter activity] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] GO:1990570 [GDP-mannose transmembrane transport] Show all	196 aa 21.9 kDa	No	7
TMEM241-012 ENSP00000463348 ENST00000582336	J3QL29 [Direct mapping] Transmembrane protein 241 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005338 [nucleotide-sugar transmembrane transporter activity] GO:0006486 [protein glycosylation] GO:0015297 [antiporter activity] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] GO:1990570 [GDP-mannose transmembrane transport] Show all	188 aa 20.8 kDa	No	6
TMEM241-201 ENSP00000440152 ENST00000542162	F5GXY7 [Direct mapping] Putative vertebrate vrg4-like nucleotide-sugar transporter truncated variant2; Transmembrane protein 241 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005338 [nucleotide-sugar transmembrane transporter activity] GO:0006486 [protein glycosylation] GO:0008643 [carbohydrate transport] GO:0015297 [antiporter activity] GO:0016021 [integral component of membrane] GO:0098656 [anion transmembrane transport] GO:1990570 [GDP-mannose transmembrane transport] Show all	149 aa 16.8 kDa	No	4

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.