Tissue expression of SPX - Summary - The Human Protein Atlas

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SPX

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SPX
Gene description	Spexin hormone
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (adipose tissue, placenta)
GTEx:	Tissue enhanced (hypothalamus)
FANTOM5:	Tissue enhanced (pancreas)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, placenta)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (hypothalamus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pancreas)

GENE INFORMATION
Gene name	SPX (HGNC Symbol)
Synonyms	C12orf39, MGC10946, NPQ, spexin
Description	Spexin hormone (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p12.1
Chromosome location (bp)	21526307 - 21537377
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134548 (version 83.38)
Entrez gene	80763
UniProt	Q9BT56 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BT56
Antibodypedia	SPX antibodies

PROTEIN BROWSER

SPX-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPX-001 ENSP00000256969 ENST00000256969	Q9BT56 [Direct mapping] Spexin Spexin-1 Spexin-2 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0003084 [positive regulation of systemic arterial blood pressure] GO:0005184 [neuropeptide hormone activity] GO:0005615 [extracellular space] GO:0010459 [negative regulation of heart rate] GO:0030133 [transport vesicle] GO:0031765 [type 2 galanin receptor binding] GO:0031766 [type 3 galanin receptor binding] GO:0032099 [negative regulation of appetite] GO:0035814 [negative regulation of renal sodium excretion] GO:0044539 [long-chain fatty acid import] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0051930 [regulation of sensory perception of pain] Show all	116 aa 13.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.