Tissue expression of PRH2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PRH2
Gene description	Proline-rich protein HaeIII subfamily 2
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (salivary gland)
GTEx:	Group enriched (esophagus, testis)
FANTOM5:	Tissue enriched (salivary gland)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)

GENE INFORMATION
Gene name	PRH2 (HGNC Symbol)
Synonyms	Pr
Description	Proline-rich protein HaeIII subfamily 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]
Chromosome	12
Cytoband	p13.2
Chromosome location (bp)	10929236 - 10932341
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134551 (version 83.38)
Entrez gene	5555
UniProt	P02810 (UniProt - Evidence at protein level)
neXtProt	NX_P02810
Antibodypedia	PRH2 antibodies

PROTEIN BROWSER

PRH2-001	PRH2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRH2-001 ENSP00000379682 ENST00000396400	P02810 [Direct mapping] Salivary acidic proline-rich phosphoprotein 1/2 Salivary acidic proline-rich phosphoprotein 1/2 Salivary acidic proline-rich phosphoprotein 3/4 Peptide P-C Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] Show all	166 aa 17 kDa	Yes	0
PRH2-002 ENSP00000371271 ENST00000381847	P02810 [Direct mapping] Salivary acidic proline-rich phosphoprotein 1/2 Salivary acidic proline-rich phosphoprotein 1/2 Salivary acidic proline-rich phosphoprotein 3/4 Peptide P-C Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] Show all	166 aa 17 kDa	Yes	0