Expression of CCDC64 in cancer - Summary

GENERAL INFORMATION
Gene name	CCDC64
Gene description	Coiled-coil domain containing 64
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (hTCEpi, SCLC-21H)
HPA (normal tissue):	Tissue enhanced (kidney, skin)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Membranous expression in subset of renal tubules and in glandular cells of epididymis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA061116
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in stomach cancer (favourable), renal cancer (favourable), head and neck cancer (favourable), cervical cancer (favourable) and liver cancer (unfavourable).
Stomach cancer p<0.001 Renal cancer p<0.001 Head and neck cancer p<0.001 Cervical cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA061116

GENE INFORMATION
Gene name	CCDC64 (HGNC Symbol)
Synonyms	FLJ26450
Description	Coiled-coil domain containing 64 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.23
Chromosome location (bp)	119989869 - 120094494
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135127 (version 83.38)
Entrez gene	92558
UniProt	Q6ZP65 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZP65
Antibodypedia	CCDC64 antibodies

PROTEIN BROWSER

CCDC64-001	CCDC64-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC64-001 ENSP00000380690 ENST00000397558	Q6ZP65 [Direct mapping] Bicaudal D-related protein 1 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0017137 [Rab GTPase binding] GO:0031175 [neuron projection development] GO:0034452 [dynactin binding] GO:0055107 [Golgi to secretory granule transport] Show all	573 aa 64.8 kDa	No	0
CCDC64-011 ENSP00000447477 ENST00000548673	H0YHP2 [Direct mapping] Bicaudal D-related protein 1 Show all	Predicted intracellular proteins Show all		291 aa 33.1 kDa	No	0