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RINT1

GENERAL INFORMATION

Gene name

 RINT1

Gene description

 RAD50 interactor 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Approved based on 1 antibody.
HPA019875
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PROGNOSTIC SUMMARY
Prognostic marker in thyroid cancer (unfavourable).
Thyroid cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA019875

GENE INFORMATION

Gene name

 RINT1 (HGNC Symbol)

Synonyms

 FLJ11785, RINT-1

Description

 RAD50 interactor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 7

Cytoband

 q22.3

Chromosome location (bp)

 105532085 - 105567677

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000135249 (version 83.38)

Entrez gene

 60561

UniProt

 Q6NUQ1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6NUQ1

Antibodypedia

 RINT1 antibodies

PROTEIN BROWSER
RINT1-001
RINT1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RINT1-001
ENSP00000257700
ENST00000257700
Q6NUQ1 [Direct mapping]
RAD50-interacting protein 1
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0007049 [cell cycle]
GO:0015031 [protein transport]
GO:0048193 [Golgi vesicle transport]
GO:0060628 [regulation of ER to Golgi vesicle-mediated transport]
GO:0070939 [Dsl1p complex]
GO:1902504 [regulation of signal transduction involved in mitotic G2 DNA damage checkpoint]
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 792 aa
90.6 kDa 		No 0
RINT1-003
ENSP00000417954
ENST00000493041
C9J5S3 [Direct mapping]
RAD50-interacting protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 143 aa
16.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.