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Several melanomas showed moderate to strong cytoplasmic positivity. Few prostate cancers showed moderate immunoreactivity. Other cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
TSPAN31 (HGNC Symbol)
Synonyms
SAS
Description
Tetraspanin 31 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]