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NMBR

GENERAL INFORMATION

Gene name

 NMBR

Gene description

 Neuromedin B receptor

Protein class

 G-protein coupled receptors
Plasma proteins
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Group enriched (fallopian tube, testis)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 NMBR (HGNC Symbol)

Synonyms

 BB1

Description

 Neuromedin B receptor (HGNC Symbol)

Entrez gene summary

 Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008]

Chromosome

 6

Cytoband

 q24.1

Chromosome location (bp)

 142058330 - 142088799

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000135577 (version 83.38)

Entrez gene

 4829

UniProt

 P28336 (UniProt - Evidence at protein level)

neXtProt

 NX_P28336

Antibodypedia

 NMBR antibodies

PROTEIN BROWSER
NMBR-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NMBR-001
ENSP00000258042
ENST00000258042
P28336 [Direct mapping]
Neuromedin-B receptor
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G-protein coupled receptors
   GPCRs excl olfactory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Plasma proteins
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GO:0004930 [G-protein coupled receptor activity]
GO:0004946 [bombesin receptor activity]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
GO:0031989 [bombesin receptor signaling pathway]
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 390 aa
43.4 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.