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RAB11FIP5

GENERAL INFORMATION

Gene name

 RAB11FIP5

Gene description

 RAB11 family interacting protein 5 (class I)

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 High expression in spermatogonia, sinusoids in spleen and renal distal tubules.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA036406 , HPA036407
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and ovarian cancer (unfavourable).
Renal cancer p<0.001
Ovarian cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036406
HPA036407

GENE INFORMATION

Gene name

 RAB11FIP5 (HGNC Symbol)

Synonyms

 GAF1, KIAA0857, pp75, RIP11

Description

 RAB11 family interacting protein 5 (class I) (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p13.2

Chromosome location (bp)

 73073382 - 73156721

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000135631 (version 83.38)

Entrez gene

 26056

UniProt

 Q9BXF6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BXF6

Antibodypedia

 RAB11FIP5 antibodies

PROTEIN BROWSER
RAB11FIP5-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB11FIP5-001
ENSP00000258098
ENST00000258098
Q9BXF6 [Direct mapping]
Rab11 family-interacting protein 5
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000139 [Golgi membrane]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005769 [early endosome]
GO:0005794 [Golgi apparatus]
GO:0005815 [microtubule organizing center]
GO:0017137 [Rab GTPase binding]
GO:0030141 [secretory granule]
GO:0030658 [transport vesicle membrane]
GO:0031901 [early endosome membrane]
GO:0035773 [insulin secretion involved in cellular response to glucose stimulus]
GO:0043015 [gamma-tubulin binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0045055 [regulated secretory pathway]
GO:0055037 [recycling endosome]
GO:0055038 [recycling endosome membrane]
GO:0070164 [negative regulation of adiponectin secretion]
GO:0071468 [cellular response to acidic pH]
GO:2000008 [regulation of protein localization to cell surface]
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 653 aa
70.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.