Expression of TSGA10 in cancer - Summary - The Human Protein Atlas

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TSGA10

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TSGA10
Gene description	Testis specific, 10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (RPTEC TERT1)
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several different tissue types including testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 2 antibodies. HPA036879 , HPA036880
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036879	HPA036880

GENE INFORMATION
Gene name	TSGA10 (HGNC Symbol)
Synonyms	CEP4L, CT79
Description	Testis specific, 10 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q11.2
Chromosome location (bp)	98997261 - 99154964
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135951 (version 83.38)
Entrez gene	80705
UniProt	Q9BZW7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BZW7
Antibodypedia	TSGA10 antibodies

PROTEIN BROWSER

TSGA10-001	TSGA10-002	TSGA10-003	TSGA10-005	TSGA10-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSGA10-001 ENSP00000377123 ENST00000393483	Q9BZW7 [Direct mapping] Testis-specific gene 10 protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005737 [cytoplasm] GO:0007283 [spermatogenesis] GO:0030031 [cell projection assembly] GO:0031514 [motile cilium] GO:0031965 [nuclear membrane] GO:0043005 [neuron projection] Show all	698 aa 81.4 kDa	No	0
TSGA10-002 ENSP00000347161 ENST00000355053	Q9BZW7 [Direct mapping] Testis-specific gene 10 protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005737 [cytoplasm] GO:0007283 [spermatogenesis] GO:0031965 [nuclear membrane] Show all	698 aa 81.4 kDa	No	0
TSGA10-003 ENSP00000377122 ENST00000393482	F8WA32 [Direct mapping] Testis-specific gene 10 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		690 aa 80.4 kDa	No	0
TSGA10-005 ENSP00000386508 ENST00000409564	B8ZZZ9 [Direct mapping] Testis-specific gene 10 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		620 aa 72.3 kDa	No	0
TSGA10-007 ENSP00000386956 ENST00000410001	Q9BZW7 [Direct mapping] Testis-specific gene 10 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005737 [cytoplasm] GO:0007283 [spermatogenesis] GO:0031965 [nuclear membrane] Show all	698 aa 81.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.