Expression of EPC2 in cancer - Summary - The Human Protein Atlas

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EPC2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	EPC2
Gene description	Enhancer of polycomb homolog 2 (Drosophila)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA036759
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036759

GENE INFORMATION
Gene name	EPC2 (HGNC Symbol)
Synonyms	DKFZP566F2124
Description	Enhancer of polycomb homolog 2 (Drosophila) (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q23.1
Chromosome location (bp)	148644440 - 148787568
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135999 (version 83.38)
Entrez gene	26122
UniProt	Q52LR7 (UniProt - Evidence at protein level)
neXtProt	NX_Q52LR7
Antibodypedia	EPC2 antibodies

PROTEIN BROWSER

EPC2-001	EPC2-002	EPC2-003	EPC2-004	EPC2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EPC2-001 ENSP00000258484 ENST00000258484	Q52LR7 [Direct mapping] Enhancer of polycomb homolog 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006281 [DNA repair] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0016568 [chromatin modification] GO:0032777 [Piccolo NuA4 histone acetyltransferase complex] Show all	807 aa 91.1 kDa	No	0
EPC2-002 ENSP00000380569 ENST00000397424	C9J1X4 [Direct mapping] Enhancer of polycomb homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0032777 [Piccolo NuA4 histone acetyltransferase complex] Show all	160 aa 19.2 kDa	No	0
EPC2-003 ENSP00000387097 ENST00000409654	E9PBA8 [Direct mapping] Enhancer of polycomb homolog 2 Show all	MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0032777 [Piccolo NuA4 histone acetyltransferase complex] Show all	121 aa 14.2 kDa	No	0
EPC2-004 ENSP00000395431 ENST00000449013	H7C0K5 [Direct mapping] Enhancer of polycomb homolog 2 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0032777 [Piccolo NuA4 histone acetyltransferase complex] Show all	126 aa 14.9 kDa	No	0
EPC2-006 ENSP00000415543 ENST00000457184	E7ETK1 [Direct mapping] Enhancer of polycomb homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0032777 [Piccolo NuA4 histone acetyltransferase complex] Show all	160 aa 19 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.