Expression of PWP1 in cancer - Summary - The Human Protein Atlas

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PWP1

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	PWP1
Gene description	PWP1 homolog, endonuclein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable), renal cancer (unfavourable) and head and neck cancer (unfavourable).
Liver cancer p<0.001 Renal cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	PWP1 (HGNC Symbol)
Synonyms	IEF-SSP-9502
Description	PWP1 homolog, endonuclein (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q23.3
Chromosome location (bp)	107685732 - 107713167
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136045 (version 83.38)
Entrez gene	11137
UniProt	Q13610 (UniProt - Evidence at protein level)
neXtProt	NX_Q13610
Antibodypedia	PWP1 antibodies

PROTEIN BROWSER

PWP1-001	PWP1-005	PWP1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PWP1-001 ENSP00000387365 ENST00000412830	Q13610 [Direct mapping] Periodic tryptophan protein 1 homolog A0A024RBH5 [Target identity:100%; Query identity:100%] PWP1 homolog (S. cerevisiae), isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] GO:0006351 [transcription, DNA-templated] Show all	501 aa 55.8 kDa	No	0
PWP1-005 ENSP00000445249 ENST00000541166	B4DJV5 [Direct mapping] Periodic tryptophan protein 1 homolog; cDNA FLJ51513, highly similar to Periodic tryptophan protein 1 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0005794 [Golgi apparatus] Show all	439 aa 49 kDa	No	0
PWP1-006 ENSP00000447770 ENST00000547995	F8VZ56 [Direct mapping] Periodic tryptophan protein 1 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		98 aa 11.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.