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Several cases of colorectal, breast, cervical, urothelial and liver cancers displayed moderate cytoplasmic positivity. Remaining cases were weakly stained or negative.
A majority of cancer tissues were negative. Occasional cases of liver, pancreatic, renal and stomach cancers showed strong cytoplasmic immunoreactivity.
GENE INFORMATION
Gene name
THSD1 (HGNC Symbol)
Synonyms
TMTSP
Description
Thrombospondin, type I, domain containing 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009]