Fields »
ABOUT
HELP
BLOG
NUDT15

GENERAL INFORMATION

Gene name

 NUDT15

Gene description

 Nudix (nucleoside diphosphate linked moiety X)-type motif 15

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA038969
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 NUDT15 (HGNC Symbol)

Synonyms

 FLJ10956, MTH2

Description

 Nudix (nucleoside diphosphate linked moiety X)-type motif 15 (HGNC Symbol)

Entrez gene summary

Chromosome

 13

Cytoband

 q14.2

Chromosome location (bp)

 48037567 - 48047222

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136159 (version 83.38)

Entrez gene

 55270

UniProt

 Q9NV35 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NV35

Antibodypedia

 NUDT15 antibodies

PROTEIN BROWSER
NUDT15-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NUDT15-001
ENSP00000258662
ENST00000258662
Q9NV35 [Direct mapping]
Probable 8-oxo-dGTP diphosphatase NUDT15
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005829 [cytosol]
GO:0006203 [dGTP catabolic process]
GO:0008413 [8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity]
GO:0016787 [hydrolase activity]
GO:0034656 [nucleobase-containing small molecule catabolic process]
GO:0035539 [8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity]
GO:0044281 [small molecule metabolic process]
GO:0046872 [metal ion binding]
GO:0055086 [nucleobase-containing small molecule metabolic process]
Show all
 164 aa
18.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.