Tissue expression of TNS3 - Summary - The Human Protein Atlas

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TNS3

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TNS3
Gene description	Tensin 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Membranous and cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA055338 , HPA056015
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TNS3 (HGNC Symbol)
Synonyms	FLJ13732, H_NH0549I23.2, TEM6, TENS1
Description	Tensin 3 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	p12.3
Chromosome location (bp)	47275154 - 47582558
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136205 (version 83.38)
Entrez gene	64759
UniProt	Q68CZ2 (UniProt - Evidence at protein level)
neXtProt	NX_Q68CZ2
Antibodypedia	TNS3 antibodies

PROTEIN BROWSER

TNS3-001	TNS3-003	TNS3-005	TNS3-006	TNS3-010	TNS3-012	TNS3-013	TNS3-014	TNS3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TNS3-001 ENSP00000312143 ENST00000311160	Q68CZ2 [Direct mapping] Tensin-3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005925 [focal adhesion] GO:0008284 [positive regulation of cell proliferation] GO:0016477 [cell migration] GO:0048286 [lung alveolus development] Show all	1445 aa 155.3 kDa	No	0
TNS3-003 ENSP00000414358 ENST00000457718	E9PCX8 [Direct mapping] Tensin-3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005925 [focal adhesion] GO:0035556 [intracellular signal transduction] GO:0046872 [metal ion binding] Show all	1250 aa 133.9 kDa	No	0
TNS3-005 ENSP00000396914 ENST00000450444	C9JHU5 [Direct mapping] Tensin-3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] GO:0046872 [metal ion binding] Show all	544 aa 60 kDa	No	0
TNS3-006 ENSP00000389285 ENST00000442536	Q68CZ2 [Direct mapping] Tensin-3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005925 [focal adhesion] Show all	250 aa 28 kDa	No	0
TNS3-010 ENSP00000387990 ENST00000428457	H7BZ64 [Direct mapping] Tensin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		21 aa 2.3 kDa	No	0
TNS3-012 ENSP00000407464 ENST00000434451	C9JUW5 [Direct mapping] Tensin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0035556 [intracellular signal transduction] GO:0046872 [metal ion binding] Show all	114 aa 12.5 kDa	No	0
TNS3-013 ENSP00000409415 ENST00000415929	C9JTD0 [Direct mapping] Tensin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		138 aa 15.6 kDa	No	0
TNS3-014 ENSP00000388142 ENST00000413551	C9JWN9 [Direct mapping] Tensin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		108 aa 12.4 kDa	No	0
TNS3-201 ENSP00000388318 ENST00000458317	Q68CZ2 [Direct mapping] Tensin-3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005925 [focal adhesion] Show all	250 aa 28 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.