Expression of SPDYE1 in cancer - Summary - The Human Protein Atlas

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SPDYE1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SPDYE1
Gene description	Speedy/RINGO cell cycle regulator family member E1
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 2 antibodies. HPA044799 , HPA051750
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044799	HPA051750

GENE INFORMATION
Gene name	SPDYE1 (HGNC Symbol)
Synonyms	Ringo1, SPDYE, WBSCR19
Description	Speedy/RINGO cell cycle regulator family member E1 (HGNC Symbol)
Entrez gene summary	This gene is located at chromosome 7p13 which is close to the Williams Beuren syndrome chromosome region 7q11.23. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p13
Chromosome location (bp)	44000889 - 44010122
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136206 (version 83.38)
Entrez gene	285955
UniProt	Q8NFV5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NFV5
Antibodypedia	SPDYE1 antibodies

PROTEIN BROWSER

SPDYE1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPDYE1-001 ENSP00000258704 ENST00000258704	Q8NFV5 [Direct mapping] Speedy protein E1 Show all	Predicted intracellular proteins Disease related genes Show all	GO:0019901 [protein kinase binding] GO:0045859 [regulation of protein kinase activity] Show all	336 aa 40.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.