Expression of ABHD17C in cancer - Summary - The Human Protein Atlas

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ABHD17C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD17C
Gene description	Abhydrolase domain containing 17C
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in selected tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA048890
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA048890

GENE INFORMATION
Gene name	ABHD17C (HGNC Symbol)
Synonyms	FAM108C1
Description	Abhydrolase domain containing 17C (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q25.1
Chromosome location (bp)	80679684 - 80755621
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136379 (version 83.38)
Entrez gene	58489
UniProt	Q6PCB6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6PCB6
Antibodypedia	ABHD17C antibodies

PROTEIN BROWSER

ABHD17C-001	ABHD17C-003	ABHD17C-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD17C-001 ENSP00000258884 ENST00000258884	Q6PCB6 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17C Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	329 aa 35.8 kDa	No	0
ABHD17C-003 ENSP00000452778 ENST00000558464	Q6PCB6 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17C Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	295 aa 32 kDa	No	0
ABHD17C-005 ENSP00000453923 ENST00000560609	H0YN98 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17C Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.