Expression of TEX2 in cancer - Summary - The Human Protein Atlas

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TEX2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TEX2
Gene description	Testis expressed 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues, including spermatids in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA020648
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PROGNOSTIC SUMMARY
Prognostic marker in colorectal cancer (favourable).
Colorectal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA020648

GENE INFORMATION
Gene name	TEX2 (HGNC Symbol)
Synonyms	HT008, KIAA1738, TMEM96
Description	Testis expressed 2 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q23.3
Chromosome location (bp)	64147227 - 64263301
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136478 (version 83.38)
Entrez gene	55852
UniProt	Q8IWB9 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IWB9
Antibodypedia	TEX2 antibodies

PROTEIN BROWSER

TEX2-001	TEX2-002	TEX2-003	TEX2-004	TEX2-006	TEX2-007	TEX2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TEX2-001 ENSP00000463001 ENST00000584379	Q8IWB9 [Direct mapping] Testis-expressed sequence 2 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0006665 [sphingolipid metabolic process] GO:0007165 [signal transduction] GO:0016021 [integral component of membrane] Show all	1127 aa 125.3 kDa	No	2
TEX2-002 ENSP00000258991 ENST00000258991	Q8IWB9 [Direct mapping] Testis-expressed sequence 2 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0006665 [sphingolipid metabolic process] GO:0007165 [signal transduction] GO:0016021 [integral component of membrane] Show all	1134 aa 126 kDa	No	2
TEX2-003 ENSP00000462665 ENST00000583097	Q8IWB9 [Direct mapping] Testis-expressed sequence 2 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0006665 [sphingolipid metabolic process] GO:0007165 [signal transduction] GO:0016021 [integral component of membrane] Show all	1127 aa 125.3 kDa	No	2
TEX2-004 ENSP00000462230 ENST00000583501	J3KRZ8 [Direct mapping] Testis-expressed sequence 2 protein Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		626 aa 71 kDa	No	0
TEX2-006 ENSP00000463286 ENST00000583922	J3QKY0 [Direct mapping] Testis-expressed sequence 2 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		52 aa 5.9 kDa	No	0
TEX2-007 ENSP00000462210 ENST00000583738	J3KRY2 [Direct mapping] Testis-expressed sequence 2 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		42 aa 4.6 kDa	No	0
TEX2-201 ENSP00000479308 ENST00000615733	A0A087WVA8 [Direct mapping] Testis-expressed sequence 2 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1127 aa 125.4 kDa	No	2

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.