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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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NIPSNAP3A
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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

NIPSNAP3A

Gene description

Nipsnap homolog 3A (C. elegans)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

Caution, targets protein from more than one gene. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA042491
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA042491

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most cancer tissues showed weak to moderate cytoplasmic positivity. A few colorectal and endometrial cancers were strongly stained. Several testis cancers along with few liver and renal cancers were negative.

GENE INFORMATION

Gene name

NIPSNAP3A (HGNC Symbol)

Synonyms

DKFZp564D177, FLJ13953, HSPC299, MGC14553

Description

Nipsnap homolog 3A (C. elegans) (HGNC Symbol)

Entrez gene summary

NIPSNAP3A belongs to a family of proteins with putative roles in vesicular transport (Buechler et al., 2004 [PubMed 15177564]).[supplied by OMIM, Mar 2008]

Chromosome

9

Cytoband

q31.1

Chromosome location (bp)

104747688 - 104760122

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136783 (version 83.38)

Entrez gene

25934

UniProt

Q9UFN0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UFN0

Antibodypedia

NIPSNAP3A antibodies

PROTEIN BROWSER

NIPSNAP3A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NIPSNAP3A-001
ENSP00000363899
ENST00000374767
Q9UFN0 [Direct mapping]
Protein NipSnap homolog 3A
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   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
Show all
247 aa
28.5 kDa
No 0

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The Human Protein Atlas project is funded
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