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Rare case of malignant melanoma displayed moderate cytoplasmic staining. Remaining cancer tissues were weakly stained or generally negative.
GENE INFORMATION
Gene name
TMOD1 (HGNC Symbol)
Synonyms
D9S57E, ETMOD, TMOD
Description
Tropomodulin 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]