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ZFP37

GENERAL INFORMATION

Gene name

 ZFP37

Gene description

 ZFP37 zinc finger protein

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA049112
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PROGNOSTIC SUMMARY
Prognostic marker in glioma (favourable).
Glioma p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA049112

GENE INFORMATION

Gene name

 ZFP37 (HGNC Symbol)

Synonyms

 ZNF906

Description

 ZFP37 zinc finger protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

 9

Cytoband

 q32

Chromosome location (bp)

 113038380 - 113056759

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136866 (version 83.38)

Entrez gene

 7539

UniProt

 Q9Y6Q3 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9Y6Q3

Antibodypedia

 ZFP37 antibodies

PROTEIN BROWSER
ZFP37-001
ZFP37-002
ZFP37-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZFP37-001
ENSP00000363344
ENST00000374227
Q9Y6Q3 [Direct mapping]
Zinc finger protein 37 homolog
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
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GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0046872 [metal ion binding]
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 630 aa
71.2 kDa 		No 0
ZFP37-002
ENSP00000452552
ENST00000553380
Q9Y6Q3 [Direct mapping]
Zinc finger protein 37 homolog
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0046872 [metal ion binding]
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 645 aa
72.9 kDa 		No 0
ZFP37-003
ENSP00000451310
ENST00000555206
Q9Y6Q3 [Direct mapping]
Zinc finger protein 37 homolog
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0046872 [metal ion binding]
Show all
 631 aa
71.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.