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STX17

GENERAL INFORMATION

Gene name

 STX17

Gene description

 Syntaxin 17

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA001204
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA001204

GENE INFORMATION

Gene name

 STX17 (HGNC Symbol)

Synonyms

 FLJ20651

Description

 Syntaxin 17 (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 q31.1

Chromosome location (bp)

 99906633 - 99970341

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136874 (version 83.38)

Entrez gene

 55014

UniProt

 P56962 (UniProt - Evidence at protein level)

neXtProt

 NX_P56962

Antibodypedia

 STX17 antibodies

PROTEIN BROWSER
STX17-001
STX17-002
STX17-003
STX17-006
STX17-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STX17-001
ENSP00000259400
ENST00000259400
P56962 [Direct mapping]
Syntaxin-17
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000149 [SNARE binding]
GO:0000421 [autophagosome membrane]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006906 [vesicle fusion]
GO:0007030 [Golgi organization]
GO:0012505 [endomembrane system]
GO:0012507 [ER to Golgi transport vesicle membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019901 [protein kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030868 [smooth endoplasmic reticulum membrane]
GO:0030897 [HOPS complex]
GO:0031201 [SNARE complex]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0034497 [protein localization to pre-autophagosomal structure]
GO:0044233 [ER-mitochondrion membrane contact site]
GO:0048278 [vesicle docking]
GO:0097111 [endoplasmic reticulum-Golgi intermediate compartment organization]
GO:0097352 [autophagosome maturation]
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 302 aa
33.4 kDa 		No 2
STX17-002
ENSP00000435981
ENST00000525640
P56962 [Direct mapping]
Syntaxin-17
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000149 [SNARE binding]
GO:0000421 [autophagosome membrane]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006906 [vesicle fusion]
GO:0007030 [Golgi organization]
GO:0012505 [endomembrane system]
GO:0012507 [ER to Golgi transport vesicle membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019903 [protein phosphatase binding]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030868 [smooth endoplasmic reticulum membrane]
GO:0030897 [HOPS complex]
GO:0031201 [SNARE complex]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0034497 [protein localization to pre-autophagosomal structure]
GO:0044233 [ER-mitochondrion membrane contact site]
GO:0048278 [vesicle docking]
GO:0097111 [endoplasmic reticulum-Golgi intermediate compartment organization]
GO:0097352 [autophagosome maturation]
Show all
 302 aa
33.4 kDa 		No 2
STX17-003
ENSP00000433484
ENST00000534052
P56962 [Direct mapping]
Syntaxin-17
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000149 [SNARE binding]
GO:0000421 [autophagosome membrane]
GO:0005484 [SNAP receptor activity]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0005829 [cytosol]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006906 [vesicle fusion]
GO:0007030 [Golgi organization]
GO:0012505 [endomembrane system]
GO:0012507 [ER to Golgi transport vesicle membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016192 [vesicle-mediated transport]
GO:0019903 [protein phosphatase binding]
GO:0030134 [ER to Golgi transport vesicle]
GO:0030868 [smooth endoplasmic reticulum membrane]
GO:0030897 [HOPS complex]
GO:0031201 [SNARE complex]
GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane]
GO:0034497 [protein localization to pre-autophagosomal structure]
GO:0044233 [ER-mitochondrion membrane contact site]
GO:0048278 [vesicle docking]
GO:0097111 [endoplasmic reticulum-Golgi intermediate compartment organization]
GO:0097352 [autophagosome maturation]
Show all
 302 aa
33.4 kDa 		No 2
STX17-006
ENSP00000434547
ENST00000526607
E9PJW1 [Direct mapping]
Syntaxin-17
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0012505 [endomembrane system]
GO:0016021 [integral component of membrane]
GO:0048278 [vesicle docking]
Show all
 41 aa
5 kDa 		No 0
STX17-007
ENSP00000433694
ENST00000531035
E9PJW1 [Direct mapping]
Syntaxin-17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006906 [vesicle fusion]
GO:0012505 [endomembrane system]
GO:0016021 [integral component of membrane]
GO:0048278 [vesicle docking]
Show all
 41 aa
5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.