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ANP32B

GENERAL INFORMATION

Gene name

 ANP32B

Gene description

 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Pending external verification.

Reliability score

 Supported based on 2 antibodies.
HPA063133 , HPA067561
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA063133
HPA067561

GENE INFORMATION

Gene name

 ANP32B (HGNC Symbol)

Synonyms

 APRIL, PHAPI2, SSP29

Description

 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 q22.33

Chromosome location (bp)

 97983361 - 98015943

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136938 (version 83.38)

Entrez gene

 10541

UniProt

 Q92688 (UniProt - Evidence at protein level)

neXtProt

 NX_Q92688

Antibodypedia

 ANP32B antibodies

PROTEIN BROWSER
ANP32B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ANP32B-001
ENSP00000345848
ENST00000339399
Q92688 [Direct mapping]
Acidic leucine-rich nuclear phosphoprotein 32 family member B
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0001944 [vasculature development]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006334 [nucleosome assembly]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0021591 [ventricular system development]
GO:0042393 [histone binding]
GO:0045596 [negative regulation of cell differentiation]
GO:0046827 [positive regulation of protein export from nucleus]
GO:0048839 [inner ear development]
GO:0060021 [palate development]
GO:0070062 [extracellular exosome]
GO:0070063 [RNA polymerase binding]
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 251 aa
28.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.