Fields »
ABOUT
HELP
BLOG
ARHGEF39

GENERAL INFORMATION

Gene name

 ARHGEF39

Gene description

 Rho guanine nucleotide exchange factor (GEF) 39

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA061299
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (favourable).
Ovarian cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA061299

GENE INFORMATION

Gene name

 ARHGEF39 (HGNC Symbol)

Synonyms

 C9orf100, FLJ14642

Description

 Rho guanine nucleotide exchange factor (GEF) 39 (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 p13.3

Chromosome location (bp)

 35658875 - 35675866

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000137135 (version 83.38)

Entrez gene

 84904

UniProt

 Q8N4T4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N4T4

Antibodypedia

 ARHGEF39 antibodies

PROTEIN BROWSER
ARHGEF39-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGEF39-001
ENSP00000367638
ENST00000378387
Q8N4T4 [Direct mapping]
Rho guanine nucleotide exchange factor 39
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005089 [Rho guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0030335 [positive regulation of cell migration]
GO:0035023 [regulation of Rho protein signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 335 aa
38.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.