Cell atlas - YIPF3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

YIPF3

premium

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS CUSTOM DATA

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Nucleoplasm

Human cell
	Golgi Apparatus
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	YIPF3
Gene description	Yip1 domain family, member 3
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (validated)
Additional location	In addition localized to the Nucleoplasm (supported)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA014859 , HPA063699
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the nucleoplasm.

Main location

Golgi apparatus (validated)

Additional location

Nucleoplasm (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA014859	A-431	Golgi apparatus
	HPA014859	A-431	Vesicles
	HPA014859	U-2 OS	No staining
	HPA014859	U-251 MG	No staining
	HPA063699	MCF7	Golgi apparatus
	HPA063699	SH-SY5Y	Nucleoplasm
	HPA063699	SH-SY5Y	Golgi apparatus
	HPA063699	U-2 OS	Nucleoplasm
	HPA063699	U-2 OS	Golgi apparatus

CUSTOM DATA


	Toggle channels

Thumbnail	Antibody	Cell line	Assay	Description
	HPA063699	U-2 OS	Image	Co-localization with the cis-Golgi marker GM130/GOLGA2 (RRID:AB_398141) after the treatment of U-2 OS cells with brefeldin A (5 ug/ml) for 30 minutes to disrupt the ER to Golgi transport; GOLGA2 localizes together with proteins associated with the Golgi-matrix (PMID: 8557739). YIPF3 is a Golgi-matrix protein, as it co-localizes with the Golgi-matrix marker GOLGA2 after the treatment with BFA.
	HPA063699	U-2 OS	Image	Co-localization with the cis-Golgi marker GM130/GOLGA2 (RRID:AB_398141) for a refined protein localization within the Golgi apparatus in U-2 OS cells. YIPF3 localizes to the Golgi apparatus, but is only detected in the cis-Golgi compartment.

GENE INFORMATION
Gene name	YIPF3 (HGNC Symbol)
Synonyms	C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1
Description	Yip1 domain family, member 3 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	43511827 - 43516990
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137207 (version 83.38)
Entrez gene	25844
UniProt	Q9GZM5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9GZM5
Antibodypedia	YIPF3 antibodies

PROTEIN BROWSER

YIPF3-003	YIPF3-012	YIPF3-017	YIPF3-018	YIPF3-020

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YIPF3-003 ENSP00000361499 ENST00000372422	Q9GZM5 [Direct mapping] Protein YIPF3 Protein YIPF3, 36 kDa form III Show all	Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030133 [transport vesicle] GO:0030154 [cell differentiation] GO:0043231 [intracellular membrane-bounded organelle] Show all	350 aa 38.2 kDa	No	5
YIPF3-012 ENSP00000425494 ENST00000506469	E7EQR8 [Direct mapping] Protein YIPF3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0043231 [intracellular membrane-bounded organelle] Show all	356 aa 38.9 kDa	No	5
YIPF3-017 ENSP00000423544 ENST00000500090	H0Y9A1 [Direct mapping] Protein YIPF3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	136 aa 15.2 kDa	No	2
YIPF3-018 ENSP00000421094 ENST00000511831	D6RGY8 [Direct mapping] Protein YIPF3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		109 aa 12.3 kDa	No	0
YIPF3-020 ENSP00000421461 ENST00000503972	D6RFI3 [Direct mapping] Protein YIPF3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] Show all	262 aa 28.8 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.