Expression of YIPF3 in cancer - Summary - The Human Protein Atlas

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YIPF3

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	YIPF3
Gene description	Yip1 domain family, member 3
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression with a granular pattern.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA014859 , HPA063699
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA014859	HPA063699

GENE INFORMATION
Gene name	YIPF3 (HGNC Symbol)
Synonyms	C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1
Description	Yip1 domain family, member 3 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	43511827 - 43516990
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137207 (version 83.38)
Entrez gene	25844
UniProt	Q9GZM5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9GZM5
Antibodypedia	YIPF3 antibodies

PROTEIN BROWSER

YIPF3-003	YIPF3-012	YIPF3-017	YIPF3-018	YIPF3-020

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YIPF3-003 ENSP00000361499 ENST00000372422	Q9GZM5 [Direct mapping] Protein YIPF3 Protein YIPF3, 36 kDa form III Show all	Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030133 [transport vesicle] GO:0030154 [cell differentiation] GO:0043231 [intracellular membrane-bounded organelle] Show all	350 aa 38.2 kDa	No	5
YIPF3-012 ENSP00000425494 ENST00000506469	E7EQR8 [Direct mapping] Protein YIPF3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0043231 [intracellular membrane-bounded organelle] Show all	356 aa 38.9 kDa	No	5
YIPF3-017 ENSP00000423544 ENST00000500090	H0Y9A1 [Direct mapping] Protein YIPF3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	136 aa 15.2 kDa	No	2
YIPF3-018 ENSP00000421094 ENST00000511831	D6RGY8 [Direct mapping] Protein YIPF3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		109 aa 12.3 kDa	No	0
YIPF3-020 ENSP00000421461 ENST00000503972	D6RFI3 [Direct mapping] Protein YIPF3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] Show all	262 aa 28.8 kDa	No	4

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.