Tissue expression of SLC22A23 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SLC22A23

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SLC22A23
Gene description	Solute carrier family 22, member 23
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA014697
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	SLC22A23 (HGNC Symbol)
Synonyms	C6orf85, FLJ22174
Description	Solute carrier family 22, member 23 (HGNC Symbol)
Entrez gene summary	SLC22A23 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
Chromosome	6
Cytoband	p25.2
Chromosome location (bp)	3268962 - 3457022
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137266 (version 83.38)
Entrez gene	63027
UniProt	A1A5C7 (UniProt - Evidence at protein level)
neXtProt	NX_A1A5C7
Antibodypedia	SLC22A23 antibodies

PROTEIN BROWSER

SLC22A23-001	SLC22A23-002	SLC22A23-005	SLC22A23-006	SLC22A23-007	SLC22A23-009	SLC22A23-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC22A23-001 ENSP00000369653 ENST00000380298	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	361 aa 38 kDa	No	6
SLC22A23-002 ENSP00000410245 ENST00000436008	C9J4Z0 [Direct mapping] Solute carrier family 22 member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	694 aa 74.6 kDa	No	>9
SLC22A23-005 ENSP00000419463 ENST00000490273	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	405 aa 44.8 kDa	No	8
SLC22A23-006 ENSP00000385028 ENST00000406686	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	686 aa 73.7 kDa	No	>9
SLC22A23-007 ENSP00000418134 ENST00000485307	H7C4T9 [Direct mapping] Solute carrier family 22 member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	440 aa 48.7 kDa	No	9
SLC22A23-009 ENSP00000369657 ENST00000380302	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	405 aa 44.8 kDa	No	8
SLC22A23-010 ENSP00000418985 ENST00000467177	C9IZW5 [Direct mapping] Solute carrier family 22 member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	386 aa 43.3 kDa	No	9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.