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FOXF2
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

FOXF2

Gene description

Forkhead box F2

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (BJ hTERT+, HEK93, U-2197)
HPA (normal tissue):Mixed

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed
0.0102030405060708090FPKMBreast cancer (BRCA)Cervical cancer (CESC)Colorectal cancer (COAD,READ)Endometrial cancer (UCEC)Glioma (GBM)Head and neck cancer (HNSC)Liver cancer (LIHC)Lung cancer (LUAD,LUSC)Melanoma (SKCM)Ovarian cancer (OV)Pancreatic cancer (PAAD)Prostate cancer (PRAD)Renal cancer (KICH,KIRC,KIRP)Stomach cancer (STAD)Testis cancer (TGCT)Thyroid cancer (THCA)Urothelial cancer (BLCA)

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

FOXF2 (HGNC Symbol)

Synonyms

FKHL6, FREAC2

Description

Forkhead box F2 (HGNC Symbol)

Entrez gene summary

FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p25.3

Chromosome location (bp)

1389834 - 1395597

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137273 (version 83.38)

Entrez gene

2295

UniProt

Q12947 (UniProt - Evidence at protein level)

neXtProt

NX_Q12947

Antibodypedia

FOXF2 antibodies

PROTEIN BROWSER

FOXF2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXF2-001
ENSP00000259806
ENST00000259806
Q12947 [Direct mapping]
Forkhead box protein F2
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0001837 [epithelial to mesenchymal transition]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0008134 [transcription factor binding]
GO:0030198 [extracellular matrix organization]
GO:0042249 [establishment of planar polarity of embryonic epithelium]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048566 [embryonic digestive tract development]
GO:0048596 [embryonic camera-type eye morphogenesis]
GO:0048806 [genitalia development]
GO:0060021 [palate development]
Show all
444 aa
46 kDa
No 0

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