Expression of TTC29 in cancer - Summary - The Human Protein Atlas

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TTC29

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TTC29
Gene description	Tetratricopeptide repeat domain 29
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Cell line enhanced (ASC TERT1, U-266/70, U-87 MG)
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expression in a few tissues, including ciliated cells in fallopian tube.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 2 antibodies. HPA037006 , HPA061473
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037006	HPA061473

GENE INFORMATION
Gene name	TTC29 (HGNC Symbol)
Synonyms	NYD-SP14
Description	Tetratricopeptide repeat domain 29 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q31.22
Chromosome location (bp)	146706638 - 146945882
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137473 (version 83.38)
Entrez gene	83894
UniProt	Q8NA56 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NA56
Antibodypedia	TTC29 antibodies

PROTEIN BROWSER

TTC29-001	TTC29-002	TTC29-006	TTC29-007	TTC29-201	TTC29-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TTC29-001 ENSP00000423505 ENST00000513335	G5E9Z5 [Direct mapping] NYD-SP14 protein, isoform CRA_c; Tetratricopeptide repeat protein 29 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	501 aa 58 kDa	No	0
TTC29-002 ENSP00000425778 ENST00000504425	E7EQ14 [Direct mapping] Tetratricopeptide repeat protein 29 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	474 aa 55 kDa	No	0
TTC29-006 ENSP00000423646 ENST00000515315	D6R945 [Direct mapping] Tetratricopeptide repeat protein 29 Show all	Predicted intracellular proteins Show all		93 aa 10.7 kDa	No	0
TTC29-007 ENSP00000425665 ENST00000502319	D6RJF6 [Direct mapping] Tetratricopeptide repeat protein 29 Show all	Predicted intracellular proteins Show all		26 aa 2.9 kDa	No	0
TTC29-201 ENSP00000316740 ENST00000325106	Q8NA56 [Direct mapping] Tetratricopeptide repeat protein 29 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	475 aa 55.1 kDa	No	0
TTC29-202 ENSP00000381861 ENST00000398886	H7BYT6 [Direct mapping] Tetratricopeptide repeat protein 29 Show all	Predicted intracellular proteins Show all		319 aa 37.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.