Tissue expression of PARP6 - Summary - The Human Protein Atlas

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PARP6

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PARP6
Gene description	Poly (ADP-ribose) polymerase family, member 6
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA026991
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	PARP6 (HGNC Symbol)
Synonyms	pART17
Description	Poly (ADP-ribose) polymerase family, member 6 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q23
Chromosome location (bp)	72241181 - 72272999
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137817 (version 83.38)
Entrez gene	56965
UniProt	Q2NL67 (UniProt - Evidence at transcript level)
neXtProt	NX_Q2NL67
Antibodypedia	PARP6 antibodies

PROTEIN BROWSER

PARP6-001	PARP6-008	PARP6-010	PARP6-011	PARP6-019	PARP6-023	PARP6-201	PARP6-202	PARP6-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PARP6-001 ENSP00000456348 ENST00000569795	Q2NL67 [Direct mapping] Poly [ADP-ribose] polymerase 6 A0A024R5Z4 [Target identity:100%; Query identity:100%] Poly (ADP-ribose) polymerase family, member 6, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	630 aa 71.1 kDa	No	0
PARP6-008 ENSP00000455815 ENST00000567974	H3BQK2 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	564 aa 63.8 kDa	No	0
PARP6-010 ENSP00000403265 ENST00000419739	F5H3B4 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	553 aa 62.3 kDa	No	0
PARP6-011 ENSP00000457862 ENST00000568360	H3BUY2 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		73 aa 8.3 kDa	No	0
PARP6-019 ENSP00000457187 ENST00000566844	H3BTI3 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		26 aa 3 kDa	No	0
PARP6-023 ENSP00000456749 ENST00000569173	H3BSK7 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		80 aa 8.9 kDa	No	0
PARP6-201 ENSP00000260376 ENST00000260376	Q2NL67 [Direct mapping] Poly [ADP-ribose] polymerase 6 J7MDH3 [Target identity:100%; Query identity:100%] PARP-6-B1 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	518 aa 58.5 kDa	No	0
PARP6-202 ENSP00000287196 ENST00000287196	Q2NL67 [Direct mapping] Poly [ADP-ribose] polymerase 6 A0A024R5Z4 [Target identity:100%; Query identity:100%] Poly (ADP-ribose) polymerase family, member 6, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	630 aa 71.1 kDa	No	0
PARP6-203 ENSP00000484561 ENST00000616176	A0A087X1Y8 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		440 aa 49.6 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.