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RSL24D1

GENERAL INFORMATION

Gene name

 RSL24D1

Gene description

 Ribosomal L24 domain containing 1

Protein class

 Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Mainly nucleolar expression in most cell types.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification. Cytoplasmic positivity observed and disregarded.

Reliability score

 Supported based on 2 antibodies.
HPA062724 , HPA063392
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Testis cancer

STAINING SUMMARY
HPA062724
HPA063392

GENE INFORMATION

Gene name

 RSL24D1 (HGNC Symbol)

Synonyms

 C15orf15, HRP-L30-iso, L30, RPL24, RPL24L

Description

 Ribosomal L24 domain containing 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012]

Chromosome

 15

Cytoband

 q21.3

Chromosome location (bp)

 55180806 - 55197067

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000137876 (version 83.38)

Entrez gene

 51187

UniProt

 Q9UHA3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UHA3

Antibodypedia

 RSL24D1 antibodies

PROTEIN BROWSER
RSL24D1-001
RSL24D1-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RSL24D1-001
ENSP00000260443
ENST00000260443
Q9UHA3 [Direct mapping]
Probable ribosome biogenesis protein RLP24
A0A024R5U8 [Target identity:100%; Query identity:100%]
Chromosome 15 open reading frame 15, isoform CRA_a
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Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000027 [ribosomal large subunit assembly]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006412 [translation]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044822 [poly(A) RNA binding]
GO:1902626 [assembly of large subunit precursor of preribosome]
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 163 aa
19.6 kDa 		No 0
RSL24D1-004
ENSP00000454492
ENST00000569386
H3BMQ2 [Direct mapping]
Probable ribosome biogenesis protein RLP24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0042254 [ribosome biogenesis]
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 66 aa
8.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.