We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cancer tissues exhibited weak to moderate cytoplasmic immunoreactivity. Few cases of liver, prostate, renal, endometrial and cervical cancers were strongly stained.
GENE INFORMATION
Gene name
FNBP1L (HGNC Symbol)
Synonyms
C1orf39, FLJ20275, TOCA1
Description
Formin binding protein 1-like (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]