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Prostate cancers demonstrated strong cytoplasmic immunoreactivity, while several cases of endometrial, renal and gastric cancers showed moderate immunoreactivity. Remaining cancers were in general weakly stained or negative.
GENE INFORMATION
Gene name
ADCY3 (HGNC Symbol)
Synonyms
AC3
Description
Adenylate cyclase 3 (HGNC Symbol)
Entrez gene summary
This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. [provided by RefSeq, Jul 2008]