Tissue expression of CENPO - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	CENPO
Gene description	Centromere protein O
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Tissue enhanced (testis)
FANTOM5:	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION
Gene name	CENPO (HGNC Symbol)
Synonyms	CENP-O, MGC11266
Description	Centromere protein O (HGNC Symbol)
Entrez gene summary	This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	24793136 - 24822376
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000138092 (version 83.38)
Entrez gene	79172
UniProt	Q9BU64 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BU64
Antibodypedia	CENPO antibodies

PROTEIN BROWSER

CENPO-001	CENPO-002	CENPO-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CENPO-001 ENSP00000370214 ENST00000380834	Q9BU64 [Direct mapping] Centromere protein O Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000776 [kinetochore] GO:0000777 [condensed chromosome kinetochore] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0006334 [nucleosome assembly] GO:0007264 [small GTPase mediated signal transduction] GO:0034080 [CENP-A containing nucleosome assembly] GO:0034508 [centromere complex assembly] Show all	300 aa 33.8 kDa	No	0
CENPO-002 ENSP00000417787 ENST00000473706	Q9BU64 [Direct mapping] Centromere protein O Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000776 [kinetochore] GO:0000777 [condensed chromosome kinetochore] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0006334 [nucleosome assembly] GO:0007264 [small GTPase mediated signal transduction] GO:0034080 [CENP-A containing nucleosome assembly] GO:0034508 [centromere complex assembly] Show all	294 aa 33 kDa	No	0
CENPO-201 ENSP00000260662 ENST00000260662	Q9BU64 [Direct mapping] Centromere protein O Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000776 [kinetochore] GO:0000777 [condensed chromosome kinetochore] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005829 [cytosol] GO:0006334 [nucleosome assembly] GO:0007264 [small GTPase mediated signal transduction] GO:0034080 [CENP-A containing nucleosome assembly] GO:0034508 [centromere complex assembly] Show all	300 aa 33.8 kDa	No	0