Expression of CEP55 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CEP55

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CEP55
Gene description	Centrosomal protein 55kDa
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA023430
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), liver cancer (unfavourable), pancreatic cancer (unfavourable), lung cancer (unfavourable) and stomach cancer (favourable).
Renal cancer p<0.001 Liver cancer p<0.001 Pancreatic cancer p<0.001 Lung cancer p<0.001 Stomach cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023430

GENE INFORMATION
Gene name	CEP55 (HGNC Symbol)
Synonyms	C10orf3, CT111, FLJ10540
Description	Centrosomal protein 55kDa (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q23.33
Chromosome location (bp)	93496632 - 93529092
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000138180 (version 83.38)
Entrez gene	55165
UniProt	Q53EZ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q53EZ4
Antibodypedia	CEP55 antibodies

PROTEIN BROWSER

CEP55-001	CEP55-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CEP55-001 ENSP00000360540 ENST00000371485	Q53EZ4 [Direct mapping] Centrosomal protein of 55 kDa Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000281 [mitotic cytokinesis] GO:0000920 [cell separation after cytokinesis] GO:0005515 [protein binding] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0016020 [membrane] GO:0030496 [midbody] GO:0032154 [cleavage furrow] GO:0045171 [intercellular bridge] GO:0045184 [establishment of protein localization] Show all	464 aa 54.2 kDa	No	0
CEP55-002 ENSP00000389150 ENST00000445435	H0Y432 [Direct mapping] Centrosomal protein of 55 kDa Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		208 aa 24.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.