Expression of CDK15 in cancer - Summary - The Human Protein Atlas

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CDK15

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CDK15
Gene description	Cyclin-dependent kinase 15
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, HMC-1, LHCN-M2)
HPA (normal tissue):	Tissue enhanced (epididymis, ovary)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA015786
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA015786

GENE INFORMATION
Gene name	CDK15 (HGNC Symbol)
Synonyms	ALS2CR7, PFTAIRE2, PFTK2
Description	Cyclin-dependent kinase 15 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q33.1
Chromosome location (bp)	201790461 - 201895550
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000138395 (version 83.38)
Entrez gene	65061
UniProt	Q96Q40 (UniProt - Evidence at protein level)
neXtProt	NX_Q96Q40
Antibodypedia	CDK15 antibodies

PROTEIN BROWSER

CDK15-001	CDK15-003	CDK15-006	CDK15-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDK15-001 ENSP00000260967 ENST00000260967	Q96Q40 [Direct mapping] Cyclin-dependent kinase 15 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0046872 [metal ion binding] GO:0051726 [regulation of cell cycle] Show all	384 aa 43.6 kDa	No	0
CDK15-003 ENSP00000386901 ENST00000410091	Q96Q40 [Direct mapping] Cyclin-dependent kinase 15 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0046872 [metal ion binding] GO:0051726 [regulation of cell cycle] Show all	384 aa 43.6 kDa	No	0
CDK15-006 ENSP00000406472 ENST00000450471	Q96Q40 [Direct mapping] Cyclin-dependent kinase 15 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0046872 [metal ion binding] GO:0051726 [regulation of cell cycle] Show all	429 aa 48.3 kDa	No	0
CDK15-007 ENSP00000412775 ENST00000434439	Q96Q40 [Direct mapping] Cyclin-dependent kinase 15 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0046872 [metal ion binding] GO:0051726 [regulation of cell cycle] Show all	400 aa 45 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.