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CXCL9

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GENERAL INFORMATION

Gene name

 CXCL9

Gene description

 Chemokine (C-X-C motif) ligand 9

Protein class

 Cancer-related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 CXCL9 (HGNC Symbol)

Synonyms

 CMK, crg-10, Humig, MIG, SCYB9

Description

 Chemokine (C-X-C motif) ligand 9 (HGNC Symbol)

Entrez gene summary

 This antimicrobial gene encodes a protein thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Sep 2014]

Chromosome

 4

Cytoband

 q21.1

Chromosome location (bp)

 76001275 - 76007488

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000138755 (version 83.38)

Entrez gene

 4283

UniProt

 Q07325 (UniProt - Evidence at protein level)

neXtProt

 NX_Q07325

Antibodypedia

 CXCL9 antibodies

PROTEIN BROWSER
CXCL9-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CXCL9-001
ENSP00000354901
ENST00000264888
Q07325 [Direct mapping]
C-X-C motif chemokine 9
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Show all
GO:0002690 [positive regulation of leukocyte chemotaxis]
GO:0005125 [cytokine activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0006935 [chemotaxis]
GO:0006952 [defense response]
GO:0006954 [inflammatory response]
GO:0006955 [immune response]
GO:0006968 [cellular defense response]
GO:0007165 [signal transduction]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007267 [cell-cell signaling]
GO:0008009 [chemokine activity]
GO:0009897 [external side of plasma membrane]
GO:0010818 [T cell chemotaxis]
GO:0030816 [positive regulation of cAMP metabolic process]
GO:0032496 [response to lipopolysaccharide]
GO:0042127 [regulation of cell proliferation]
GO:0043950 [positive regulation of cAMP-mediated signaling]
GO:0045663 [positive regulation of myoblast differentiation]
GO:0048248 [CXCR3 chemokine receptor binding]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051607 [defense response to virus]
GO:0070098 [chemokine-mediated signaling pathway]
GO:1901741 [positive regulation of myoblast fusion]
Show all
 125 aa
14 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.