Tissue expression of MARCH9 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	MARCH9
Gene description	Membrane-associated ring finger (C3HC4) 9
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	MARCH9 (HGNC Symbol)
Synonyms	FLJ36578, RNF179
Description	Membrane-associated ring finger (C3HC4) 9 (HGNC Symbol)
Entrez gene summary	MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM, Apr 2010]
Chromosome	12
Cytoband	q14.1
Chromosome location (bp)	57755098 - 57760407
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139266 (version 83.38)
Entrez gene	92979
UniProt	Q86YJ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q86YJ5
Antibodypedia	MARCH9 antibodies

PROTEIN BROWSER

MARCH9-001	MARCH9-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MARCH9-001 ENSP00000266643 ENST00000266643	Q86YJ5 [Direct mapping] E3 ubiquitin-protein ligase MARCH9 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005765 [lysosomal membrane] GO:0005795 [Golgi stack] GO:0005802 [trans-Golgi network] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] Show all	346 aa 37.8 kDa	No	2
MARCH9-002 ENSP00000446758 ENST00000548358	Q86YJ5 [Direct mapping] E3 ubiquitin-protein ligase MARCH9 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005765 [lysosomal membrane] GO:0005795 [Golgi stack] GO:0005802 [trans-Golgi network] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] Show all	233 aa 25.9 kDa	No	2