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Malignant tissues showed weak to moderate cytoplasmic positivity. Several cases of testicular, cervical and renal cancers were negative.
GENE INFORMATION
Gene name
PTPRQ (HGNC Symbol)
Synonyms
DFNB84
Description
Protein tyrosine phosphatase, receptor type, Q (HGNC Symbol)
Entrez gene summary
This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation. Mutations at this locus have been linked to autosomal recessive deafness. [provided by RefSeq, Mar 2014]