Expression of C12orf10 in cancer - Summary - The Human Protein Atlas

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C12orf10

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C12orf10
Gene description	Chromosome 12 open reading frame 10
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and cytoplasmic expression, most abundant in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. HPA038627
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038627

GENE INFORMATION
Gene name	C12orf10 (HGNC Symbol)
Synonyms	Gamm1, MYG, MYG1
Description	Chromosome 12 open reading frame 10 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.13
Chromosome location (bp)	53299686 - 53307177
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139637 (version 83.38)
Entrez gene	60314
UniProt	Q9HB07 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HB07
Antibodypedia	C12orf10 antibodies

PROTEIN BROWSER

C12orf10-001	C12orf10-003	C12orf10-007	C12orf10-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C12orf10-001 ENSP00000267103 ENST00000267103	Q9HB07 [Direct mapping] UPF0160 protein MYG1, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0035641 [locomotory exploration behavior] GO:0043473 [pigmentation] GO:0070062 [extracellular exosome] Show all	376 aa 42.4 kDa	Yes	0
C12orf10-003 ENSP00000450270 ENST00000548632	F8VQQ3 [Direct mapping] UPF0160 protein MYG1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		301 aa 33.8 kDa	No	0
C12orf10-007 ENSP00000455319 ENST00000547864	H3BPH3 [Direct mapping] UPF0160 protein MYG1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		130 aa 14.3 kDa	No	0
C12orf10-008 ENSP00000448433 ENST00000549488	F8VR84 [Direct mapping] UPF0160 protein MYG1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] Show all	213 aa 24.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.