Expression of ANKRD52 in cancer - Summary - The Human Protein Atlas

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ANKRD52

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANKRD52
Gene description	Ankyrin repeat domain 52
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and/or cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA043815
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043815

GENE INFORMATION
Gene name	ANKRD52 (HGNC Symbol)
Synonyms	FLJ34236, PP6-ARS-C
Description	Ankyrin repeat domain 52 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.3
Chromosome location (bp)	56237807 - 56258391
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139645 (version 83.38)
Entrez gene	283373
UniProt	Q8NB46 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NB46
Antibodypedia	ANKRD52 antibodies

PROTEIN BROWSER

ANKRD52-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD52-001 ENSP00000267116 ENST00000267116	Q8NB46 [Direct mapping] Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	1076 aa 115.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.