Tissue expression of KRT71 - Summary - The Human Protein Atlas

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KRT71

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	KRT71
Gene description	Keratin 71, type II
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (breast, epididymis)
GTEx:	Tissue enriched (skin)
FANTOM5:	Not detected

Protein evidence

Evidence at protein level

Protein expression

Highly expressed in the inner root sheath of hair follicles.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. External characterization data supports antibody staining.
Reliability score	Supported based on 1 antibody. HPA049404
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Hair

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (breast, epididymis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (skin)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Not detected

GENE INFORMATION
Gene name	KRT71 (HGNC Symbol)
Synonyms	K6IRS1, KRT6IRS, KRT6IRS1
Description	Keratin 71, type II (HGNC Symbol)
Entrez gene summary	Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
Chromosome	12
Cytoband	q13.13
Chromosome location (bp)	52543909 - 52553147
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139648 (version 83.38)
Entrez gene	112802
UniProt	Q3SY84 (UniProt - Evidence at protein level)
neXtProt	NX_Q3SY84
Antibodypedia	KRT71 antibodies

PROTEIN BROWSER

KRT71-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT71-001 ENSP00000267119 ENST00000267119	Q3SY84 [Direct mapping] Keratin, type II cytoskeletal 71 Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005882 [intermediate filament] GO:0031069 [hair follicle morphogenesis] GO:0045095 [keratin filament] GO:0045109 [intermediate filament organization] GO:0070062 [extracellular exosome] Show all	523 aa 57.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.